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Hasriadi; Wasana, P.W.D.; Vajragupta, O.; Rojsitthisak, P.; Towiwat, P. Automated home-cage monitoring as a potential measure of sickness behaviors and pain-like behaviors in LPS-treated mice Plos One, Open Access Research Article, 27 August 2021 Full Article |
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Li, J.; Ma, K.; Yi, D.; Oh, C.; Chen, D. Nociceptive behavioural assessments in mouse models of temporomandibular joint disorders International Journal of Oral Science IJOS, 12, Article number: 26 (2020), 29 September 2020 Full Article |
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La Porta, C.; Tappe-Theodor, A. Differential impact of psychological and psychophysical stress on low back pain in mice PAIN, July 2020, Volume 161, Issue 7, Pages 1442-1458, July 2020 Abstract |
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Park, H.; Choi, Y.; Jung, H.;Kim, S.; Lee, S.; Han, H.; Kweon, H.; Kang, S.; Sim, W.S.; Koopmans, F.; Yang, E.; Kim, H.; Smit, A.B. ; Bae, Y.C.; Kim, E. Splice-dependent trans-synaptic PTPδ–IL1RAPL1 interaction regulates synapse formation and non-REM sleep The EMBO Journal (2020)39:e104150, 29 April 2020 Full Article |
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Yoo, T.; Kim, S-G.; Yang, S.H.; Kim, H.; Kim, E.; Kim, S.Y. A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum Molecular Autism, 11, Article number: 19 (2020), 12 March 2020 Full Article |
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Kosel, F.; Pelley, J.M.S.; Franklin, T.B. Behavioural and psychological symptoms of dementia in mouse models of Alzheimer's disease-related pathology: Running title: BPSD in Alzheimer's disease models Neuroscience & Biobehavioral Reviews, Volume 112, Pages 634-647, May 2020 (online 15 February 2020) Abstract |
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Borbélyová, V.; Janišová, K.; MysliveÄek, J.; Riljak, V. Sex-Related Differences in Locomotion and Climbing of C57Bl/6NTac Mice in a Novel Environment Psychological Research, 68 (Suppl. 3), 26 September 2019 Full Article |
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MihalÄíková,L.; Ochozková, A.L.; Šlamberová, R. Effect of Methamphetamine Exposure on Sexual Behavior and Locomotor Activity of Adult Male Rats Psychological Research, 68 (Suppl. 3), 14 September 2019 Full Article |
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Goncharov, N. V.; Terpilowski, M. A.; Kudryavtsev, I. V.; Serebryakova, M. K.; Belinskaia, D. A.; Sobolev, V. E.; Shmurak, V. I.; Korf, E. A.; Avdonin, P. V. The Rat (Rattus norvegicus) as a Model Object for Acute Organophosphate Poisoning. 2. A System Analysis of the Efficacy of Green Tea Extract in Preventing Delayed Effects of Poisoning Comparative and Ontogenic Physiology, 3 August 2019 Abstract |
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Marwari S; Poulsen, A.; Shih, N.; Lakshminarayanan, R.; Kini, R.M.; Johannes, C.W.; Dymock, B.W.; Dawe, G.S. Intranasal administration of a stapled relaxinâ€3 mimetic has anxiolytic†and antidepressantâ€like activity in rats British Journal of Pharmacology, Research Paper, First published Online 20 June 2019 Abstract |
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Yoo, Y-E.; Yoo,T.; Lee,S.; Lee, J.; Kim, D.; Han, H-M.; Bae, Y-C.; Kim, E. Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal Excitability and Seizure Susceptibility Frontiers in Molecular Neuroscience, 18 June 2019, Original Research Article, Published Online 18 June 2019 Full article |
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Ambrozkiewicz, M.C.; Ripamonti, S.; Borisova, E.; Schwark, M.; Schaub, T.; Altas, B.; Yilmaz, R.; Piepkorn, L.; Horan, S.; Jahn, O.; Dere, E.; Rosário, M.; Borck, G.; Ehrenreich, H.; Willig, K.; Rhee, JS.; Tarabykin, V.; Kawabe, H. The Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc BioRXiv, First published Online 16 June 2019 Full article |
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Ruud, J.; Alber, J.; Tokarska, A.; Engström-Ruud, L.; Nolte, H.; Biglari, N.; Lippert, R.; Lautenschlager, Ä.; CieÅ›lak, P.E.; Szumiec, Å.; Hess, M.E.; Brönneke, H.S.; Krüger, M.; Nissbrandt, H.; Korotkova, T.; Silberberg, G.; Rodriguez Parkitna, J.; Brüning, J.C. The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons Cell Reports, Volume 27, Issue 11, 11 June 2019, Pages 3182-3198 Abstract |
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Lee, H.; Shin, W.; Kim, K.; Lee, S.; Lee, E-J.; Kim, J.; Kweon, H.; Lee, E.; Park, H.; Kang, M.; Yang, E.; Kim, H.; Kim, E. NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors PLOS, Open Access, Research Article, 5 June 2019 Abstract |
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Shin, W.; Kweon, H.; Kang, R.; Kim, D.; Kim, K.; Kang, M.; Kim, S.Y.; Hwang, S.N.; Kim, J.Y.; Yang, E.; Kim, H.; Kim, E. Scn2a Haploinsufficiency in Mice Suppresses Hippocampal Neuronal Excitability, Excitatory Synaptic Drive, and Long-Term Potentiation, and Spatial Learning and Memory Frontiers Molecular Neuroscience, Original Research Article, First published Online 4 June 2019 Full Article |
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Aguiniga, L.M.; Yang, W.; Yaggie, R.E.; Schaeffer, A.J.; Klumpp, D.J. Acyloxyacyl Hydrolase Modulates Depressive-like Behaviors through Aryl Hydrocarbon Receptor American Journal of Physiology Regulatory Integrative and Comparative Physiology, 24 April 2019 Abstract |
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Valuskova, P.; Riljak, V.; Forczek, S.T.; Farar, V.; Myslivecek, J. Variability in the Drug Response of M4 Muscarinic Receptor Knockout Mice During Day and Night Time Frontiers in Pharmacology, Neuropharmacology, 18 March 2019 Full Article |
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Tappe-Theodor, A.; King, T.; Morgan, M.M. Pros and Cons of Clinically Relevant Methods to Assess Pain in Rodents Neuroscience & Biobehavioral Reviews, Volume 100, May 2019, Pages 335-343, Published online 15 March 2019 Abstract |
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Anderson, S.J.; Lockhart, J.S.; Estaki, M.; Quin, C.; Hirota, S.A.; Alston, L.; Buret, A.G.; Hancock, T.M.; Petri, B.; Gibson, D.L.; Morck, D.W. Effects of Azithromycin on Behavior, Pathologic Signs, and Changes in Cytokines, Chemokines, and Neutrophil Migration in C57BL/6 Mice Exposed to Dextran Sulfate Sodium Ingenta Connect, Comparative Medicine, Volume 69, Number 1, 1 February 2019 Abstract |
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Šlamberová, R.; Nohejlová, K.; Ochozková, A.; Mihalciková, L. What is the Role of Subcutaneous Single Injections on the Behavior of Adult Male Rats Exposed to Drugs? Physiology Research 67 (Suppl. 4): S665-S672, 2018, Volume 9, Article number: 5400 (2018), 31 December 2018 Full Article |
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Babaev,O.; Cruces-Solis, H.; Chatain, C.P.; Hammer, M.; Wenger, S.; Ali, H.; Karalis, N.; De Hoz, L.; Schlüter, O.M.; Yanagawa, Y.; Ehrenreich, H.; Taschenberger, H.; Brose, N.; Krueger-Burg, D. IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses Nature Communications, Volume 9, Article number: 5400 (2018), 20 December 2018 Full Article |
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Sambamurthy, N.; Zhou, C.; Nguyen, V.; Smalley, R.; Hankenson, K.D.; Dodge, G.R.; Scanzello, C.R. Deficiency of the pattern-recognition receptor CD14 protects against joint pathology and functional decline in a murine model of osteoarthritis Plos-One Research Article, Published: November 28, 2018 Full Article |
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Sales, L.B.; Van Esterik, J.C.J.; Hodemaekers, H.M.; Lamoree, M.H.; Hamers, T.; Van der Ven, L.T.M.; Legler, J. Analysis of Lipid Metabolism, Immune Function, and Neurobehavior in Adult C57BL/6JxFVB Mice After Developmental Exposure to di (2-ethylhexyl) Phthalate Frontiers in Endocrinology, 2018; 9: 684, Published online 21 November 2018 Full Article |
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Bgatova, N.; Solovjeva, O.; Shatskaya, S.; Taskaeva, I.; Isupov, V.; Makaro, V. Neuroprotective effects of lithium carbonate in conditions of tumor growth 2018 11th International Multiconference Bioinformatics of Genome Regulation and Structure\Systems Biology (BGRS\SB, November 2018 Abstract |
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Marešová, D.; Kozler, P.; Miletínová, E.; Zima, T.; Pokorný, J. Locomotion in young rats with induced brain cellular edema – effects of recombinant human erythropoietin Neuroendocrinology Letters Volume 39 No. 4 2018, 20 October 2018 Full Article |
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Winkler, D.; Daher, F.; Wüstefeld, L.; Hammerschmidt, K. Poggi, G.; Seelbach, A.; Krueger-Burg, D.; Vafadari, B.; Ronnenberg, A.; Liug, Y.; Kaczmarek, L.; Schlüter, O.M.; Ehrenreich, H.; Dere, A. Hypersocial behavior and biological redundancy in mice with reduced expression of PSD95 or PSD93 Behavioural Brain Research, Volume 352, 15 October 2018, Pages 35-45 Abstract |
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Yoo, T.; Cho, H.; Lee, J.; Park, H.; Yoo, Y-E.; Yang, E.; Young Kim, J.; Kim, H.; Kim, E. GABA Neuronal Deletion of Shank3 Exons 14–16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities Frontiers in Cellulair Neuroscience, 2018; 12: 341, 9 October 2018 Abstract |
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Ossato, A.; Bile, S.; Gregori, A.; Talarico, A.; Trapella, C.; Gaudio, R.M.; De-Giorgio, F.; Tagliaro, F.; Neri, M.; Fattore, L.; Marti, M. Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice Neuropharmacology Volume 141, Pages 167-180, October 2018 Abstract |
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Crespo, M.; León-Navarro, D.A.; Martín, M. Early-life hyperthermic seizures upregulate adenosine A2A receptors in the cortex and promote depressive-like behavior in adult rats Epilepsy & Behavior Volume 86, Pages 173-178, September 2018 Abstract |
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Horne, D.B.; Biswas, K.; Brown, J.; Bartberger, M.D.; Clarine, J.; Davis, C.D.; Gore, V.K.; Harried,S.; Horner, M.; Kaller, M.R.; Lehto, S.G.; Liu, Q.; Ma, V.V.; Monenschein, H.; Nguyen, T.T.; Yuan, C.C.; Youngblood, B.D.; Zhang, M.; Zhong, W.; Allen, J.R.; Chen, J.J.; Gavva, N.R. Discovery of TRPM8 Antagonist (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine Journal of Medicinal Chemistry, 2018, 61 (18), pp 8186–8201, 27 August 2018 Abstract |
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Jung, H.; Park, H.; Choi, Y.; Kang, H.; Lee, E.; Kweon, H.; Roh, J.D.; Ellegood, J.; Choi, W.; Kang, J.; Rhim, I.; Choi, S-Y.; Bae, M.; Kim, S-G.; Lee, J.; Chung, C.; Yoo, T.; Park, H.; Kim, Y.; Ha, S.; Um, S.M.; Mo, S.; Kwon, Y.; Mah, W.; Bae, Y.C.; Kim, H.; Lerch, J.P.; Paik, S-B.; Kim, E. Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice Nature Neuroscience, Volume 21, pages 1218–1228, 13 August 2018 Abstract |
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Cisar,J.S.; Weber, O.D.; Clapper, J.R.; Blankman, J.L.; Henry, C.L.; Simon, G.M.; Alexander, J.P.; Jones, T.K.; Ezekowitz, R.A.B.; O’Neill, G.P.; Grice, C.A. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders Journal of Medicinal Chemistry, 2018, Volume 61, Pages 9062−9084, 1 August 2018 Full Article |
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Eltokhi, A.; Rappold, G.; Sprengel, R. Distinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants Frontiers in Molecular Neuroscience, 2018; 11: 240, Published online 19 July 2018 Full Article |
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Um, S.M.; Ha. S.; Lee, H.; Kim, J.; Kim, K.; Shin, W.; Sul, Y.S.; Roh. J.D.; Kang, J.; Yoo, T.; Noh, Y.W.; Choi, Y.; Bae, Y.C.; Kim, E. NGL-2 Deletion Leads to Autistic-like Behaviors Responsive to NMDAR Modulation Cell Reports, Volume 23, Issue 13, Pages 3839-3851 (open access), 26 June 2018 Full Article |
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Lee, S.; Lee, E.; Kim, R.; Kim, J.; Lee, S.; Park, H.; Yang, E.; Kim, H.; Kim, E. Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice Frontiers in Molecular Neuroscience, 19 June 2018 Full Article |
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Miller, R.E.; Malfait, A. Osteoarthritis pain: What are we learning from animal models? Best Practice & Research Clinical Rheumatology, Available online 26 April 2018 Abstract |
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Polyzos, A.A.; Wood, N.I.; Williams, P.; Wipf, P.; Morton, A.J.; McMurray, C.T. XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent PlosOne Open Access Research Article, 9 April 2018 Full Article |
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Kim, R.; Kim, J.; Chung, C.; Ha, S.; Lee, S.; Lee, Yoo, Y-E.; Kim, W.; Shin, W.; Kim, E. Cell type-specific Shank2 deletion in mice leads to differential synaptic and behavioral phenotypes Journal of Neuroscience, 2684-17, 23 March 2018 Abstract |
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Dere, E.; Ronnenberg, A.; Tampe, B.; Arinrad, S.; Schmidt, M.; Zeisberg, E.; Ehrenreich, H. Cognitive, emotional and social phenotyping of mice in an observer-independent setting Neurobiology of Learning and Memory, Volume 150, April 2018, Pages 136-150, Online 21 February 2018 Abstract |
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Ashokan, A.; Hegde, A.; Balasingham, A.; Mitra, R. Housing environment influences stress-related hippocampal substrates and depression-like behavior Brain Research, Volume 1683, 15 March 2018, Pages 78–85, Online 2 February 2018 Abstract |
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Munro, G.; Petersen, S.; Jansen-Olesen, I.; Olesen, J. A unique inbred rat strain with sustained cephalic hypersensitivity as a model of chronic migraine-like pain Scientific Reportsvolume 8, Article number: 1836 (2018), Online 30 January 2018 Abstract |
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Pieper, A.A.; Friestad, G. Compositions and Methods for Treating Anxiety and Compulsive Behavior US Patent Application: US20180002295A1, University of Iowa Research Foundation (UIRF), January 2018 Abstract |
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Li, Y.; Kim, R,7, Cho, Y.S.; Kim, D. Kim, K., Roh, J.D.; Park, H.; Yang, E., Kim, S-J.; Ko, J.; Kim, H.; Bae, J-C.; Kim, E. Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response Report bioRxiv 23 January 2018 Full article |
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Marcos, J. L.; Galleguillos, D.; Pelissier, T.; Hernández, A.; Velásquez, L.; Villanueva, L.; Constandil, L. Role of the spinal TrkB-NMDA receptor link in the BDNF-induced long-lasting mechanical hyperalgesia in the rat: A behavioural study European Journal of Pain (United Kingdom), Volume 21, Issue 10, pp. 1688-1696, November 1, 2017 online Abstract |
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Šlamberová, R.; Rudá-Kucerová, J.; Babinská, Ševciková, M. Olfactory Bulbectomy in Methamphetamine-Treated Rat Mothers Induces Impairment in Somatic and Functional Development of Their Offspring Physiol. Res. 66 (Suppl. 4): S469-S479, 2017 Full article |
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Macúchová, E.; Šlamberová Does Prenatal Methamphetamine Exposure Induce Sensitization to Drugs in Adulthood? Physiol. Res. 66 (Suppl. 4): S457-S467, 2017 Full article |
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Pyavchenko, G.A.; Pugach, V.A. Novikova, N.S.; Shmarkova, L.I.; Korneva, E. A.; Nozdrin, V. I. The Content of c-Fos-Positive Neurons in the Cerebral Cortex and Striatum and Behavioral Characteristics in Rats on Cutaneous Application of Antiseptic Dorogov’s Stimulator Paste Neuroscience and Behavioral Physiology, October 2017, Volume 47, Issue 8, pp 1004–1009, October 30, 2017 online Abstract |
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Filiz, A.; Tepe, N.; Eftekhari, S.; Boran, H.E.; Dilekoz, E.; Edvinsson, L.; Bolay, H. CGRP receptor antagonist MK-8825 attenuates cortical spreading depression induced pain behavior Cephalalgia, pp. 1-9, 28 October 3, 2017 online Abstract |
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Nagarajan, N.; Jones, B.W.; West, P.J.; Marc, R.E.; Capecchi, M.R. Corticostriatal circuit defects in Hoxb8 mutant mice Molecular Psychiatry. 2017, September 26, 2017 online Abstract |
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Deepitha, S.; Michael, H.; Jagadeesh, G.; Rohini, H. A mouse model for pain and neuroplastic changes associated with pancreatic ductal adenocarcinoma Pain, Volume 158, Issue 8, page 1609–1621, August 2017Abstract |
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Neureither, F.; Stowasser, N.; Frings, S.; Mohrlen, F. Tracking of unfamiliar odors is facilitated by signal amplification through anoctamin 2 chloride channels in mouse olfactory receptor neurons Psysiological Reports 2017,5 (15), 2017, August 2017 online Full article |
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Sambamurthy, N.; Nguyen, V.;Smalley, R.; Xiao, R.; Hankenson, K.; Gan, J.; Miller, R.E.; Malfait, A.; Dodge, G.R.; Scanzello, C.R. Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis Journal of Orthopaedic Research 2017, 2 August 2017 online Abstract |
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Marcos, J.L.; Galleguillos, D.; Pelissier, T. Hernández, A.; Velásquez, L.; Villanueva, L.; Constandil, L. Role of the spinal TrkB-NMDA receptor link in the BDNF-inducedlong-lasting mechanical hyperalgesia in the rat: A behavioural study European Journal of Pain 2017, 3 July 2017 online Abstract |
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Tarrasón, G.; Carcasona, C.; Eichhorn, P.; Pérez, B.; Gavaldà, A.; Godessart, N. Characterization of the chloroquine-induced mouse model of pruritus using an automated behavioural system Experimental Dermatology 2017, 12 June 2017 online Full article |
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Neureither, F.; Ziegler, K.; Pitzer. C.; Frings, S.; Möhrlen, F. Impaired Motor Coordination and Learning in Mice Lacking Anoctamin 2 Calcium-Gated Chloride Channels Cerebellum 2017, 23 May 2017 online Full article |
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Lutter, M.; Khan, M.Z.; Satio, K.; Davis, K.C.; Kidder, I.J.; McDaniel, L.; Darbro, B.W.; Pieper, A.A.; Cui, H. The Eating-Disorder Associated HDAC4-A778T Mutation Alters Feeding Behaviors in Female Mice Biological Psychiatry,2017 May 01; 81(9): 770–777, 1 May 2017 Full article |
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Wang, W.; Li, C.; Chen, Q.; Van der Goes, M.; Hawrot, J.; Yao, A.Y.; Gao, X.; Lu, C.; Zang, Y.; Zhang, Q.; Lyman, K.; Wang, D.; Guo, B.; Wu, S.; Gerfen, C.R.; Fu, Z.; Feng, G. Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism The Journal of Clinical Investigation, Volume 127 Number 5, Pages 1978 - 1990, 1 May 2017 Full article |
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Sambamurthy, N.; Nguyen, V.; Smalley, R.; Dodge, G.; Scanzello, C. CD14 deficiency prevents subchondral bone remodeling and functional decline in a murine model of osteoarthritis Osteoarthritis and Cartilage, Volume 25, Supplement 1, Page S44, April 2017Abstract |
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Zarebska, J.M.; Chanalaris, A.; Driscoll, C.; Burleigh, A.; Miller, R.E.; Malfait, A.M.; Stott, B.; Vincent, T.L. CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy Osteoarthritis and Cartilage, Volume 25, Issue 3, Pages 406-4125, March 2017 Full Article |
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Christensen, S.L.; Petersen, S.; Sørensen, D.B.; Olesen, J.; Jansen-Olesen, I. Cilostazol induces C-fos expression in the trigeminal nucleus caudalis and behavioural changes suggestive of headache with the migraine-like feature photophobia in female rats Cephalalgia, 21 February 2017 online Abstract |
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Winkler, D.; Daher, F.; Wüstefeld, L.; Hammerschmidt, K.; Poggi, G.; Seelbach, A.; Krueger-Burg, D.; Vafadari, B.; Ronnenberg, A.; Liu, Y.;Kaczmarek, L.; Schlüter, O.M.; Ehrenreich, H.; Dere, E. Hypersocial behavior and biological redundancy in mice with reduced expression of PSD95 or PSD93 Behavioural Brain Research February 9, 2017 online Abstract |
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Ha, S.; Lee, D.; Cho, Y.S.; Chung, C.; Yoo, Y_E.; Kim, J.; Lee, J.; Kim, X.; Kim, W.; Bae, Y.C.; Tanaka-Yamamoto, K.; Kim, E. Adulthood behavioral and neurodevelopmental effects of being raised by an ambivalent mother in rats: what does not kill you makes you stronger The Journal of Neuroscience, 36(48):12129 –12143, 30 November 30 2016 Full article |
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DÖNMEZ,R.A.; CANDANSAYAR, S.; DERÄ°NÖZ, O.; GÜLBAHAR, Ö.;
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Godessart, N.; Carcasona, C.; Eichhorn, P.; Roberts, R.; Gavalda, A.; Tarrason, G. Characterization of the chloroquine-induced pruritus mouse model and its pharmacological modulation using an auomated platform Experimental Dermatology 2016; 25 (Suppl. 4): 3–51, 16 October 2016 Full Article |
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Kordas-Sz, K.; Eldering, H.; Bulthuis, R.J.A.; Román, V. Measuring sociability of mice using a novel 3-chamber set-up and algorithm of an automated animal behaviour analysis system Poster at the 29th ECNP conference Vienna, 17-20 September 2016 Poster |
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Pitzer, C.; Kuner, R.; Tappe-Theodor, A. Voluntary and evoked behavioral correlates in inflammatory pain conditions under different social housing conditions Pain Reports, Volume 1, Issue 1. p e564, August 2016 Full Article |
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Poggi, G.; Boretius, S.; Möbius, W.; Moschny, N.; Baudewig, J.; Ruhwedel, T.; Hassouna, I.; Wieser, G.L.; Werner, H.B.; Goebbels, S.; Nave, K.A.; Ehrenreich, H. Cortical Network Dysfunction Causedby a Subtle Defect of Myelination GLIA Research Article, Volume 64, Issue 11, pages 2025..2040, 29 July 2016 Full Article |
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Kumar, J.R.; Rajkumar, R.; Lee, L.C.; Dawe, G.S. Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors Neuropharmacology, Volume 110, Part A, Pages 1–14, November 2016 Full Article |
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Trueman, R.C.; Diaz. C.; Farr, T.D.; Harrison, D.J.; Fuller, A.; Tokarczuk, P.F.; Stewart, A.J.; Paisey, S.J.; Dunnett, S.B. Systematic and detailed analysis of behavioural tests in the rat middle cerebral artery occlusion model of stroke: Tests for long-term assessment Journal of Cerebral Blood Flow and Metabolism, 27 July 2016 Full Article |
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Blaker, C.L.; Clarke, E.C.; Little, C.B. Using mouse models to investigate the pathophysiology, treatment and prevention of postâ€traumatic osteoarthritis Journal of Orthopaedic Research, 28 June 2016 Abstract |
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Ginneken, V.V. The Urgent Compelling Need to Swap on a Global Scale from Indirect Mouse Calorimetry (IMC) Towards Direct Mouse Calorimetry (DMC) in Determining the Basal Metabolic Rate (BMR): A Principle of Proof Study Anatomy & Physiology, Volume 6, Issue 3, 1000223, 25 May 2016 Full Article |
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Hart, P.C.; Bergner, C.L.; Smolinsky, A.N.; Dufour, B.D.; Egan, R.J.; LaPorte, J.L.; Kalueff, A.V. Experimental Models of Anxiety for Drug Discovery and Brain Research Protocol, Mouse Models for Drug Discovery, Volume 1438 of the series Methods in Molecular Biology, pages 271-291, 6 May 2016 Abstract |
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Macúchová, E.; ŠevÄíková, M.; HrebíÄková, I.; Nohejlová, K. ; Šlamberová, R. How various drugs affect anxiety-related behavior in male and female rats prenatally exposed to methamphetamine International Journal of Developmental Neuroscience, Volume 51, Pages 1–11, June 2016 Abstract |
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Çivi, S.; Emmez, G.; Akın Dere, Ü.; Özgün Börcek, A.; Emmez, H. Effects of quercetin on chronic constriction nerve injury in an experimental rat model Acta Neurochirurgica, Volume 158, Issue 5, pages 959-965, May 2016 Abstract |
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P'yavchenko, G.A.; Shmarkova, L.I.; Nozdrin, V. I. Changes in the Number of Neurons in the Rat Motor Cortex and Movement Activity with Age Neuroscience and Behavioral Physiology, Volume 46, Issue 3, pages 270-273, March 2016 Abstract |
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Spray, S.; Edvinsson, L. Improved assessment of outcomes following transient global cerebral ischemia in mice Experimental Brain Research, pages 1-10, 25 February 2016 Abstract |
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Nichols, J.N.; Deshane, A.S.; Niedzielko, T.L.; Smith, C.D.; Floyd, C.L. Greater neurobehavioral deficits occur in adult mice after repeated, as compared to single, mild traumatic brain injury (mTBI) Behavioural Brain Research, Volume 298, Part B, Pages 111–124, 1 February 2016 Abstract |
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Muley,M.M.; Krustev, E.; McDougall, J.J. Preclinical Assessment of Inflammatory Pain CNS Neuroscience & Therapeutics 22 (2016) Pages 88–101, January 2016 Full Article |
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Babaev, O.; Botta, P.; Meyer, E.; Müller, C.; Ehrenreich, H.; Brose, N.; Lüthi, A.; Krueger-Burg, D. Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala Neuropharmacology, Volume 100, Pages 56–65, January 2016 Full Article |
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Van Esterik, J.C.J.; Verharen, H.W.; Hodemaekers, H.M.; Gremmer, E.R.; Nagarajah, B.; Kamstra, J.H.; Dollé, M.E.T.; Legler, J.; Van der Ven, L.T.M. Compound- and sex-specific effects on programming of energy and immune homeostasis in adult C57BL/6JxFVB mice after perinatal TCDD and PCB 153 Toxicology and Applied Pharmacology, Volume 289, Issue 2, Pages 262–275, 1 December 2015 Abstract |
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Kumar, J.R.; Rajkumar, R.; Farooq, U.; Lee, L.C.; Tan, F.C.K.; Dawe, G.S. Evidence of D2 receptor expression in the nucleus incertus of the rat Physiology & Behavior 151 (2015), Page 525–534, November 2015 Full Article |
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Tarrasón, G.; Carcasona, C.; Eichhorn, P.; Orellana, A.; Roberts, R.; Godessart, N.; Gavaldà, A. Characterization of the mouse model of chloroquine-induced pruritus using an automated recording system 1st International Symposium: Future in Dermatology- Inflammation, 02-03 October 2015 Full article |
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Hamilton, C.B.; Pest, M.A.; Pitelka, V.; Ratneswaran, A.; Beier, F.; Chesworth, B.M. Weight-bearing asymmetry and vertical activity differences in a rat model of post-traumatic knee osteoarthritis Osteoarthritis and Cartilage, Volume 23, Issue 7, Pages 1178–1185, July 2015 Abstract |
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Kang, J.; Kim, E. Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors Frontiers in Molecular Neuroscience, Volume8, Article 17, 1 May 2015 Full Article |
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Cui, H.; Lu, Y.; Khan, M.Z.; Anderson, R.M.; McDaniel, L.; Wilson, H.E.; Yin, T.C.; Radley, J.J.; Pieper, A.A.; Lutter, M. Behavioral Disturbances in Estrogen-Related Receptor alpha-Null Mice Cell Reports, Volume 11, Issue 3, Pages 344–350, 21 April 2015 Full Article |
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Lee, J.; Chung, C.; Ha, S.; Lee, D.; Kim, D-J.; Kim, H.; Kim, E. Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit Frontiers in Cellular Neuroscience, Volume 9, Article 94, 19 March 2015 Full Article |
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Piel, M.J.; Kroin, J.S.; Im, H. Assessment of Knee Joint Pain in Experimental Rodent Models of Osteoarthritis Osteoporosis and Osteoarthritis Methods in Molecular Biology,Volume 1226, 2015, pp 175-181 Abstract |
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Chung, W.; Choi, S.Y.; Lee, E.; Park, H.; Kang, J.; Park, H.; Choi, Y.; Lee, D.; Park, S-G.; Kim, R.; Cho, Y.S.; Choi, J.; Kim, M-W.; Lee, J.W.; Lee, S.; Rhim, I.; Jung, M.W.; Kim, D.; Bae, Y.C.; Kim, E. Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression Nature Neuroscience, Vol. 18, Page 435–443 (2015), 26 January 2015 Full Article |
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Morgan, D.A.; McDaniel, L.N.; Yin, T.; Khan,M.; Jiang, J.; Acevedo, M.R.; Walsh, S.A.; Boles Ponto, L.L.; Norris, A.W.; Lutter, M.; Rahmouni, K.; Cui, H. Regulation of Glucose Tolerance and Sympathetic Activity by MC4R Signaling in the Lateral Hypothalamus Diabetes, Jan. 2015 Full Article |
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Riljak, V.; Marešová, D.; Pokorný, J.; Jandová, K. Subconvulsive dose of kainic acid transiently increases the locomotor activity of adult Wistar rats Physiology Research, 15 October 2014 Abstract |
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Yin, T.C.; Britt, J.K.; De Jesús-Cortés, H.; Lu, Y.; Genova, R.M.; Khan, M.Z.; Voorhees, J.R.; Shao, J.; Katzman, A.C.; Huntington, P.J.; Wassink, C.; McDaniel, L.; Newell, E.A.; Dutca, L.M.; Naidoo, J.; Cui, H.; Bassuk, A.G.; Harper, M.W.; McKnight, S.I.; Ready, J.M.; Pieper, A.A. P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury Cell Reports 8, 1–10, September 25, 2014 Full Article |
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Gee, J.M.; Smith, N.A.; Fernandez, F.R.; Economo, M.N.; Brunert, D.; Rothermel, M.; Morris, S.C.; Talbot, A.; Palumbos, S.; Ichida, J.M.; Shepherd, J.D.; West, P.J.; Wachowiak, M.; Capecchi, M.R.; Wilcox, K.R.; Whiteemail, J.A.; Tvrdik, P. Imaging Activity in Neurons and Glia with a Polr2a-Based and Cre-Dependent GCaMP5G-IRES-tdTomato Reporter Mouse Neuron, Volume 83, Issue 5, p1058–1072, 3 September 2014 Full Article, Video |
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Tepe, N.; Filiz, A.; Dilekoz, E.; Akcali, D.; Sara, Y.; Charles, A.; Bolay, H. The thalamic reticular nucleus is activated by corticalspreading depression in freely moving rats: prevention byacute valproate administration European Journal of Neuroscience, 15 September 2014, pp. 1–9 Full Article |
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Sayin, A.; Derinöz, O.; Yüksel, N.; Åžahin, S.; Bolay, H. The effects of the estrus cycle and citalopram on anxiety-like behaviors and c-fos expression in rats Pharmacology Biochemistry and Behavior, September 2014, Vol. 124, Pages 180–187 Abstract |
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Macúchová, E.; Nohejlová, K.; Šlamberová, R. Gender differences in the effect of adult amphetamine on cognitive functions of rats prenatally exposed to methamphetamine Behavioural Brain Research, 15 August 2014, Volume 270, Pages 8–17 Abstract |
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Jandová, K.; Kozler, P.; Langmeier, M.; Maresová, D.; Pokorný, J.;
Riljak, V. Influence of Low-Dose Neonatal Domoic Acid on the Spontaneous Behavior of Rats in Early Adulthood Physiology Research, Volume 63 (Suppl. 4): Page 521-528, 10 August 2014 Full Article |
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Van Esterik, J.C.J.; Dollé, M.E.T.; Lamoree, M.H.; Van Leeuwen, S.P.J.; Hamers, T.; Legler, J. Van der Ven, L.T.M. Programming of metabolic effects in C57BL/6JxFVB mice by exposure to bisphenol A during gestation and lactation Toxicology, 3 July 2014, Vol. 321, Pages 40-52 Abstract |
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Kronenberg, G.; Gertz, K.; Heinz, A.; Endres, M. Of mice and men: modelling post-stroke depression experimentally British Journal of Pharmacology, 2 July 2014 Abstract |
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Yang, C.; Feng, R.; Yang, L.; Jiang, S.; Liu, N.; Yan, L. Liu, Y.; Yang, C.; Wang, K. Phenotyping age-sependent changes in the 5xFAD Alzheimer’s Disease Model mice (LB556) The Faseb Journal, April 2014, Vol. 28, No. 1, LB556 Abstract |
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Yang, C.; Feng, R.; Yang, L.; Jiang, S.; Liu, N.; Yan, L. Liu, Y.; Yang, C.; Wang, K. Phenotyping age-sependent changes in the 5xFAD Alzheimer’s Disease Model mice (LB556) Poster at APSET conference 2014 Poster |
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Šlamberová, R.; Macúchová, E.; Nohejlová, K.; Štofková, A.; JurÄoviÄová, J. Effect of Amphetamine on Adult Male and Female Rats Prenatally Exposed to Methamphetamine Prague Medical Report, April 2014, Vol. 115, No. 1–2, p. 43–59 Full article |
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Dere, E.; Winkler, D.; Ritter, C.; Ronnenberg, A.; Poggi, G.; Patzig, J.; Gernert, M.; Müller, C.; Nave, K.; Ehrenreich, H.; Werner, H.B.c Gpm6b deficiency impairs sensorimotor gating and modulates the behavioral response to a 5-HT2A/C receptor agonist Behavioral Brain Research, 22 April 2014 Abstract |
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Piel, M.J.; Kroin, J.S.; Van Wijnen, A.J.; Kc, R.; Im, H. Pain assessment in animal models of osteoarthritis Gene, 10 March 2014, Volume 557, Issue 2, Pages 184 - 188 Abstract |
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Aslihan Dönmez, R.; Duygu Kaya, F.; Derimöz, O.; Hakan Emmez, O.; Candansayar, A.; Bolay Belens, H. Behavioural and neurobiological consequences of 2 different chronic stressors in rats Turkish Journal of Medical Sciences, January 2014, Vol. 44 Full article |
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Broide, R.S.; Rubino, J.; Nicholson, G.S.; Ardila, M.C.; Brown, M.S.; Acki, K.R.; Francis, J. The rat Digit Abduction Score (DAS) assay: A physiological model for assessing botulinum neurotoxin-induced skeletal muscle paralysis Toxicon, 1 September 2013, Volume 71, Pages 18–24 Abstract |
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Jandoková, K.; Maresová, D.; Pokorný, J. Fast and Delayed Locomotor Response to Acute High-Dose Nicotine Administration in Adult Male Rats Physiological Research 62 (Suppl. 1): S81-S88, 11 July 2013, (ISSN 0862-8408 (print), ISSN 1802-9973 (online) Full article |
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Malfait, A.M.; Little, C.B.; McDougall, J.J. A commentary on modelling osteoarthritis pain in small animals Osteoarthritis and Cartilage, 15 June 2013, Volume 21, Pages 1306 -1326 Full article |
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Xu, P.; Grueter, B.A.; Britt, J.K.; McDaniel, L.; Huntington, P.J.; Hodge, R.; Tran, S.; Mason, B.L.; Lee, C.; Vong, L.; Lowell, B.B.; Malenka, R.C.; Lutter, M.; Pieper, A.A. Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice PNAS May 2013 Full article |
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Graepel, R.; Leung, G.; Wang, A.; Villemaire, M.; Jirik, F.R.; Sharkey, K.A.; McDougall, G.G.; McKay, D.M. Murine autoimmune arthritis is exaggerated by infection with the rat tapeworm, Hymenolepis diminuta International Journal for Parasitology, 11 April 2013 Abstract |
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Ritter, C. Comprehensive behavioral characterization of Gpm6b null mutants as a mouse model of depression Thesis for the Degree "Dr. of Veterinary Medicine", University of Veterinary Medicine Hannover, April 2013 Full article |
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Kozler, P.; Riljak, V.; Pokorný, J. Both Water Intoxication and Osmotic BBB Disruption Increase Brain Water Content in Rats Physiological Research 62 (Suppl. 1): S75-S80, 2013, 17 March 2013, (ISSN 0862-8408 (print), ISSN 1802-9973 (online) Full article |
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Šlamberová, R,; Macúchová, E.; Nohejlová-Deykun, K.; Schutová, B.; Hrubá, L.; Rokyta, R. Gender Differences in the Effect of Prenatal Methamphetamine Exposure and Challenge Dose of Other Drugs on Behavior of Adult Rats Physiological Research 62 (Suppl. 1): S99-S108, 2013, 11 March 2013, (ISSN 0862-8408 (print), ISSN 1802-9973 (online) Full article |
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Bachdasarian, L.; Bulthuis, R.J.A.; Molewijk. M.; Guchkov, S.; Revyakin, A. Enhanced technologies and integration parameters of pre-clinical studies Biomedicina, March 2013, No.1 Full article |
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Driscoll, C.; Burleigh, A.; Chanalaris, A.; Saklatvala, J.; and Vincent, T.L. Gender modulates the molecular response to acute joint destabilization International Journal of Experimental Pathology, 2013, 94, A1–A48 Full article |
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El-Kordi, A.; Winler, D.; Hammersmidt, K.; Kästner, A,; Krueger, D.; Ronnenberg, A.; Ritter, C.; Jatho, J.; Radyushkin, K.; Bourgerone, T.; Fischer, J. Brose, N.; Ehrenreich, H. Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism Behavioral Brain Research, November 23, 2012 Abstract |
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Miller, R.E.; Tran, P.B.; Das, R.; Ghoreishi-Haack, N.; Ren, D.; Miller, R.J.; Malfait, A. CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis PNAS, November 7, 2012 Full article |
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Machuchova, E.; Nohejlova-Deykun, K.; Nova, E.; Schutova, B.; Hruba, L.; Slamberova, R. Effect of prenatal methamphetamine exposure on sensitivity to other psychostimulants in adult male rats tested in Laboras apparatus Poster at SFN2012, October 2012 Poster |
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Krieger, M.; Both, M.; Kranig, S.A.; Pitzer, C.; Klugmann, M.; Vogt, G.; Draguhn, A.; Schneider, A. The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions Nature: Scientific Reports 2,Article number:697 - 26 September 2012 Full article |
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Vattakuzhi, Y.; Abraham, S.M.; Freidin, A.; Clark, A.R.; Horwood, N.J. Dual-specificity phosphatase 1–null mice exhibit spontaneous osteolytic disease and enhanced inflammatory osteolysis in experimental arthritis Arthritis & Rheumatism, Vol. 64, Issue 7, pages 2201–2210, July 2012 Abstract |
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Little, C.B.; Zaki, S. What constitutes an “animal model of osteoarthritis”–the need for consensus? Osteoarthritis and Cartilage - Elsevier, April 2012 Abstract |
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Šlamberová, R. Drugs in Pregnancy: the Effects on Mother and Her Progeny Physiol. Res. 61 (Suppl. 1): S123-S135, April 2012 Full article |
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Castagné, V.; Wolinsky, T.; Quinn, L.; Virley, D. Differential behavioral profiling of stimulant substances in the rat using the LABORAS™ system Pharmacology, biochemistry, and behavior, March 2012 Abstract |
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Waters, K.A.; Stean, T.O.; Hammond, B.; Virley, D.J.; Upton, N.; Kew, J.N.C.; Hussain, I. Effects of the selective 5-HT7 receptor antagonist SB-269970 in animal models of psychosis and cognition Behavioural Brain Research, Volume 228, Issue 1, 1 March 2012, Pages 211-218 Abstract |
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Schutová, B.; Hrubá, L.; Rokyta, R.; Šlamberová, R. Gender differences in behavioral changes elicited by prenatal methamphetamine exposure and application of the same drug in adulthood Developmental Psychobiology, 23 Feb. 2012, Pages xx Abstract |
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Belyaev, D.A.; Pekelis, M.M.; Fokin, Y.V.; Kazakova, L.K. The analysis of some physiological and ethological characteristics of hairless rats as new model for biomedical researches (translated from Russian) Biomedicine (Биомедицина) No.1, 2012 Abstract |
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Krieger, M. The hematopoietic cytokine Granulocyte - Macrophage Colony Stimulating Factor is involved in cognitive processing Dessertation University of Heidelberg, Germany, October 2011 Full article |
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Srinivasan, J.; Wright, R.L.; Roberts, J.; MacSweeney, C.; Marston, H.M. Ketamine-induced Behavioural and Neurochemical Effects: Simultaneous Measurements of Locomotor Activity, Extracellular Cortical Glutamate and Drug Levels in C57 Mice Poster at SFN2011 of Merck, New House, UK, October 2011 Poster |
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Floyd, C.F.; Shepard Jr., S. Characterizing the Relationship Between Blast Exposure and Mild TBI with Dynamic Modeling and Testing in a New Mouse Model Report University of Alabama (July, 2011) Full Article |
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Cazzin, C.; Piccoli, L.; Massagrande, M.; Garbati, N.; Michielin, F.; Knaus, H.G.; Ring, C.J.A.; Morrison, A.D.; Merlo-Pich, E. Rovo, Z.; Astori, S.; Lüthi, A.; Corti, C. and M. Corsi† rKv1.2 overexpression in the central medial thalamic area decreases caffeine-induced arousal Genes, Brain and Behavior, Volume xxx, pp xxx; (July 11, 2011) Full Article |
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Metris Inside View feature about Laboras of Metris b.v. Nature Magazine, 7 July 2011 Full article |
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Šlamberová, R.; Yamamotová, A.; Schutová, B.; Hrubá, L.; Pometlová, M. Impact of prenatal methamphetamine exposure on the sensitivity to the same drug in adult male rats Prague Medical Report, Vol. 112 (2011) No. 2, p. 102–114 Full article |
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Wolinsky, T.; Quinn, L.; Virley, D.; Castagné, V.; Moser, P. Behavioral profiling of stimulant after acute administration in rats using Laboras Poster at "College on Problems of Drug Dependence" (CPDD), June 18-23, 2011 Poster |
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Lynch III, J.J.; Castagné, V.; Moser, P.C.; Mittelstaft, S.W. Comparison of methods for the assessment of locomotor activity in rodent safety pharmacology studies Journal of Pharmacological and Toxicological Methods, Volume xxx, pp xxx; (March 31, 2011) Full article |
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Razzoli, M.; Carboni, L.; Andreoli, M.; Ballottari, A.; Arban, R. Different susceptibility to social defeat stress of BalbC and C57BL6/J mice Behavioural Brain Research, Volume 216, pp 100–108 (1 January 2011) Full article |
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Zambello, E.; Zanetti, L.; Hédou, G.F.; Angelici, O.; Arban, R.; Tasan, R.O.; Sperk G.; Caberlotto, L. Neuropeptide Y-Y2 receptor knockout mice: influence of genetic background on anxiety-related behaviors Neuroscience, "Article in Press" (available online 3 November 2010) Full article |
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Razzoli, M.; Carboni, L.; Andreoli, M.; Maraia, G.; Di Francesco, C.; Arban, R. Functional role of calcium-stimulated Adenylyl Cyclase 8 in adaptations to psychological stressors in the mouse: Implications for mood disorders Neuroscience, Volume 170, pp 429-440 (2010) Full article |
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Dawe, G.S.; Nagarajah, R.; Albert, R.; Casey, D.E.; Gross, K.W.; Ratty, A.K. Antipsychotic drugs dose-dependently suppress the spontaneous hyperactivity of the chakragati mouse Neuroscience 171 (2010) 162–172 (available online 17 September 2010) Full article |
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Broide, R.S.; Ardilla, C.; Aoki, K.R.; Francis, J. The LABORAS behavioral assay provides an alternative, non-lethal experimental method for the assessment of botulinum toxin systemic safety Poster at the Society for Neuroscience conference, SFN 2010 (13-17 November 2010) Abstract of Poster |
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Schutová, B.; Hrubá, L.; Rokyta, R.; Slamberová, R. Sensitivity to methamphetamine in adulthood is increased in rats prenatally exposed to the same drug Poster at the Society for Neuroscience conference, SFN 2010 (13-17 November 2010) Poster |
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Slamberová, R.; Yamamatová, A.; Hrubá, L.; Schutová, B.; Rokyta, R. Prenatal methamphetamine exposure alters the effect of methamphetamine and cocaine challenge dose on behavior and nociception in adult male rats Poster at the Society for Neuroscience conference, SFN 2010 (13-17 November 2010) Poster |
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Dawe, G.S.; Albert, R.; Ratty, K. Home cage activity monitoring reveals changes in circadian rhythm in the chakragatimouse model of aspects of schizophrenia Poster at the Society for Neuroscience conference, SFN 2010 (13-17 November 2010) Poster |
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Das, R.; Plaas, A.; Sandy, J.D.; Li, J.; Tortorella, M.D.; Malfait, A.M. Destabilization of the medial meniscus as a model for dissecting pain pathways associated with development of murine osteoarthritis Poster at 13th World Congress on Pain, IASP 2010 (1 September 2010) Abstract of Poster |
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Dahllöf, H.; Sederholm, F.; Halvarsson, L.; Täpp, V.; Jongsma Wallin, H.; Stenfors, C. Pharmacological Characterisation of the Behavioral Registration System Laboras in the Detection of Formalin-Induced Nociception Poster at 13th World Congress on Pain, IASP 2010 (1 September 2010) Poster |
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Lightowler, S.; Barratt, L.; Kennett, G. LABORAS, An automated measure of formalin paw licking behaviour and concurrent locomotor activity in rats Poster at 13th World Congress on Pain, IASP 2010 (31 August 2010) Poster |
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Wong, F.; Lee, S.H.; Atcha, Z.; Ong, A.B.O.; Pemberton, D.J.; Chen, W. Rasagiline improves learning and memory in young healthy rats Behavioural Pharmacology, Volume 21, Issue 4, pp 278-282 (2 July 2010) Full article |
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Glynn, D.; Gibson, H.E.; Harte, M.K.; Reim, K.; Jones, S.; Reynolds, G.P.; Morton, A.J. Clorgyline-mediated reversal of neurological deficits in a Complexin 2 knockout mouse Human Molecular Genetics, Volume 19, Issue 17, pp 3402–3412 (28 June 2010) Full article |
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McCann, F.E.; Palfreeman, A.C.; Andrews, M., Inglis, J.J.; Schafer, P.; Feldmann, M.; Williams, R.O.; Brennan, F.; Perocheau D.P. Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis Arthritis Research & Therapy 2010, 12:R107, (June 2, 2010) Full article |
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Chen, S.K..; Tvrdik, P.; Peden, E.; Cho, S.; Wu, S.; Spangrude, G.; Capecchi, M.R. Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice Cell 141, Pages 775-785 (May 28, 2010) Full article |
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Akcali, D.; Sayin1, A.; Sara, Y.; Bolay, H. Does single cortical spreading depression elicit pain behaviour in freely moving rats? Cephalalgia Volume .., Issue .., Pages 1-12 (March 31, 2010) Full article |
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Franek, M.; Vaculín Š. LABORAS in Pain Studies Psychiatrie (2009), 13(4), Pages 153–156 Full article |
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Wong, F. Effect of neuroinflammation on cognition and potential mechanisms involved Msc. Thesis Department of Pharmacology, National University of Singapore (2009) Full report |
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Bubenikova-Valesovaa, V.; Kacerb, P.; Syslovab, K.; Rambousekb, L.; Janovskyc, M.; Schutovad, B.; Hrubad, L.; Slamberova, R. Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring International Journal of Developmental Neuroscience Volume 27, Issue 6, Pages 525-530 (October 2009) Full article |
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Bison, S.; Carboni, L.; Arban, R.; Bate, S.; Gerrard, P.A.; Razolli, M.; Differential behavioral, physiological, and hormonal sensitivity to LPS challenge in rats International Journal of Interferon, Cytokine and Mediator Research 2009:1, page 1-13 (2009) Full article |
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Hakim, P.; Gurung, I.S.; Pedersen, T.H.; Thresher, R.; Brice, N.; Lawrence, J.; Grace, A.A.; Huang, C.L.-H. Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties Progress in Biophysics and Molecular Biology 98 (2008) 251–266 (available online 24 January 2009) Full article |
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Woolley, M.L.; Pemberton, D.J.; Bate S.; & Corti, C.; Jones, D.N.C. The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity Psychopharmacology, (2008) 196:431–440 Full article |
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Wood, N.I.; Goodman, A.O.; Van der Burg, J.M.; Gazeau, V.; Brundin, P.; Björkqvist, M.; Petersén, A.; Tabrizi, S.J.; Barker, R.A.; Morton, A.J.; Increased thirst and drinking in Huntington's disease and the R6/2 mouse Brain Research Bull, 76 (1-2):70-9 (2008) Full article |
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Inglis, J.J.; McNamee, K.E.; Chia, S.; Essex, D.; Feldmann, M.; Williams, R.O.; Hunt,S.P.; Vincent, T. Regulation of pain sensitivity in experimental osteoarthritis by the endogenous peripheral opioid system
Arthritis & Rheumatism Vol. 58, Issue 10, Pages 3110 -3119 (Sept. 2008) Full article |
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Avsaroglu, H.; Sommer, R.; Hellebrekers, L.J.; Van Zutphen, L.F.M.; Van Lith, H.A.; The effects of buprenorphine on behaviour in the ACI and BN rat inbred strains Laboratory Animals, 42 (2008), Page 171-184 Full article |
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Van der Burg, J.J.M.; Bacos, K.; Wood, N.I.; Lindqvist, A.; Wierup, N.; Woodman, B.; Wamsteeker, J.I.; Smith, R.; Deierborg, T.; Kuhar, M.J.; Bates, G.P.; Mulder, H.; Erlanson-Albertsson, C.; Morton, A.J.; Brundin, P.; Petersén, A.; Björkqvista, M. 'Increased metabolism in the R6/2 mouse model of Huntington's disease' Neurobiology of Disease, 29 (2008), Page 41-51 Full article |
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Van der Burg, J.J.M. 'Beyond the Basal Ganglia Widespread pathology in Huntington’s disease' Doctorial Thesis, Lund University, Lund, Sweden (2008), ISBN 978-91-86059-43-9 Full report |
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FranÄ›k, M.; Vaculín, Š.; Rokyta, R. 'Changes of locomotor activity in animal models of neuropathic pain' 12th World Congress on Pain, Glasgow, Scotland (August 2008) Poster |
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McAllister, C.J. 'Evaluating the efficacy of LABORAS and Intellicage for measuring circadian rhythms in the R6/2 transgenic mouse model of Huntington’s disease' FENS 2008 conference (July 2008), FENS Abstr., vol.4, 096.15, 2008 Poster |
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Hedenqvist, P. 'Anaesthesia and analgesia for surgery in rabbits and rats, a comparison of the effects of different compounds' Doctorial Thesis, Karolinska Institutet, Stockholm (2008), ISBN: 978-91-7357-578-2 Full report |
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Bachdasarian, L.; Bulthuis, R. 'The importance of the energy parameter in preclinical research' Metris b.v. (2008) Full report |
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Altun, M.; Bergman, E.; Edström, E.; Johnson, H.; Ulfhake, B. 'Behavioral impairments of the aging rat' Physiology & Behavior, Volume 92, Issue 5, 5 December 2007, Pages 911-923 Full article |
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Altun, M. 'Old-age muscle atrophy - Cellular mechanisms and behavioral consequences' Doctorial Thesis, Karolinska Institut, Stockholm, Sweden (2007), ISBN 978-91-7357-305-4 Full report |
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Nagelkerken, L.; Verzaal, P.; Lagerweij, T.; Persoon-Deen, C.; Havekes L.; Oranje, A.P. 'Human apolipoprotein C1 transgenic mice: a unique model of atopic dermatitis.' Poster (AD 2007) Full Poster |
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Avsaroglu, H.; Sommer, R.; Hellebrekers, L.J.; Van Zutphen, L.F.M.; Van Lith, H.A. 'Differences in the behavioural response to buprenorphine between the ACI and BN rat inbred strains' Poster 10th FELASA Symposium, June 11-14, 2007 Cernobbio Full Poster |
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Van Loo, P.L.P.; Kuin, N.; Sommer, R.; Avsaroglu, H.; Pham, T.; Baumans, V. 'Impact of "living apart together" on postoperative recovery of mice compared with social and individual housing.' Laboratory Animals (2007) Full article |
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Inglis, J.J.; Notley, C.; Essex, D.; Wilson, A.W.; Feldmann, M.; Anand, P.; Williams, R. 'Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of TNF blockade.' Arthritis & Rheumatism (29 November 2007) Vol 56, Issue 12, Pages 4015-4023 Full article |
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Erschbamer, M.; Pernold, K.; Olson, L. 'Inhibiting Epidermal Growth Factor Receptor Improves Structural, Locomotor, Sensory, and Bladder Recovery from Experimental Spinal Cord Injury' The Journal of Neuroscience (June 13, 2007) Vol. 27, Issue 24, Page 6428–6435 Full Article |
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Medhurst, A.D.; Briggs, M.A.; Bruton, G.; Calver, A.R.; Chessell, I.; Crook, B.;, Davis, J.B.; Davis, R.P.; Foley, A.G.; Heslop, T.; Hirst, W.D.; Medhurst, S.J.; Ociepka, S.; Ray, A.; Regan, C.M.; Sargent, B.; Schogger, J.; Stean, T.O.; Trail, B.K.; Upton, N.; White, T.; Orlek, B.; Wilson, D.M. 'Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats' Biochemical Pharmacology (15 April 2007) Vol. 73, Issue 8, Page 1182–1194 Full article |
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Chicurel, M. 'HD2006: Changes, Advances, and Good News (CAG)' Summary Report of the Heredity Disease Foundation Symposium 2006 (published February. 2007) Full report |
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Pugha, P.L.; Richardson, J.C.; Bate, S.T.; Upton, N.; Sunter, D.; 'Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease' Behavioural Brain Research (2007), Vol 178, Page 18-28 (available Jan. 2007) Full article |
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Aberg, E. 'On Regulation of Hippocampal Neurogenesis: Roles of Ethanol Intake, Physical Activity and Environment' Doctorial Thesis, Karolinska Institutet, Stockholm (2007), ISBN: 978-91-7357-439-6 Full report |
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Amaya, F.; Wang, H.; Costigan, M.; Allchorne, A.J.; Hatcher, J.P.; Egerton, J.; Stean, T.; Morisset, V.; Grose, D.; Gunthorpe, M.J.; Chessell, I.P.; Tate, S.; Green, P.J.; Woolf, C.J. 'The Voltage-Gated Sodium Channel Nav1.9 Is an Effector of Peripheral Inflammatory Pain Hypersensitivity' The Journal of Neuroscience, (December 13, 2006), Vol 26, Issue 50, Page 12852-12860 Full article |
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Quinn, L.; Steann, T.; Chapman, H.; Brown, M.; Vidgeon-Hart, M.; Upton, N.; Billinton, A.; Virley, D. 'Further Validation of LABORAS Using Various Dopaminergic Manipulations in Mice Including MPTP-Induced Nigro-Striatal Degeneration' Elsevier Journal of Neuroscience Methods, (September 2006) Full article |
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Erschbamer, M.K.; Pham, T.M.; Zwart, M.C.; Baumans, V.; Olson, L. 'Neither environmental enrichment nor voluntary wheel running enhances recovery from incomplete spinal cord injury in rats' Experimental Neurology (2006), Vol 201, Issue 1, Page 154-164 Full article |
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Zhu, S.; Pham, T.M.; Åberg, E.; Brene, S.; Winblad, B.; Mohammed, A.H.; Baumans, V. 'Neurotrophin levels and behaviour in BALB/c mice: impact of intermittent exposure to individual housing and wheel running' Behavioural Brain Research (2006), Vol 167, Issue 1, Page 1-8 Full article |
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Metris b.v. / Dr. Ellen Molewijk 'High Quality Simultaneous Measurements of Rodents Behaviour, Tracking, Physiology, Sleep Stages and Ultrasounds' Touch Briefings, Future Drug Discovery 2006, (report January 2006) Full article |
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Quinn, L.; Grundy, R.; Campbell, C.;, Collier, S.; Lawman, A.; Stean, T.; Billinton, A.; Parsons, A.; Upton, N.; Duxon, M.;, Irving, E. 'A novel behavioural registration system LABORAS and the social interaction paradigm detect long-term functional deficits following middle cerebral artery occlusion in the rat' Brain Research, (7 January 2005); Vol 1031, Issue 1, Page 118-24 Full article |
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Horwood, J.M.; Kennett, G.; Sheardown, M.J. 'A novel, automated method of measuring the Mouse behavioral satiety sequence' Poster Paradigm Therapeutics presented at EBPS 2005 in Barcelona (September 2005) Poster |
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Aberg, E.; Pham, T.; Zwart, M.; Baumans, V.; Brene, S. 'Intermittent individual housing survival of newly proliferated cells' Neuroreport / Molecular Sience, Vol 16 Issue 13, Page 1419-1422 (September 8, 2005) |
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Sommer, R.; Meijer, M.K.; Bulthuis, R.J.A.; Ohl, F.; Baumans, V. 'Simultaneous collection of behavioural and physiological data in mice: integration of LABORAS with Dataquest A.R.T. telemetry' Poster University of Utrecht presented at Measuring Behavior 2005 in Wageningen (August 2005) Poster |
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Szondiné Kordás, K.; Galgoczy, K.; Bulthuis, R.J.A.; Horvath, C.; et al. 'New automated measurement of formalin induced paw licking in rats by LABORAS system' Poster Gedeon Richter presented at the International Forum on Pain Medicine in Sofia, Bulgaria (May, 2005) Poster |
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Metris b.v. / Dr. Ellen Molewijk 'High Quality Measurements of Rodents Behaviour, Tracking and Ultrasounds Using LABORAS and SONOTRACK' Touch Briefings, Future Drug Discovery 2005, (report January 2005) Full article |
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Puustinen, K. 'Evaluation of the tail biopsy procedure on the behaviour and wellbeing of mice - a pilot study' Thesis Sveriges Lantbrukuniversitet - SLU, Uppsala (October 2004), ISSN 1650-7045 Full report |
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Augustsson, H. 'Ethoexperimental Studies of Behaviour in Wild and Laboratory Mice - Risk Assessment, Emotional Reactivity and Animal Welfare' Doctorial Thesis, Swedish University of Agricultural Sciences, Uppsala (2004), ISBN 91-576-6668-7 Full report |
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Quinn, L.; Steann, T.; Trail, B.; Duxon, M.; Stratton, S.; Billinton, A.; Upton, N. 'LABORAS: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour' Elsevier Journal of Neuroscience Methods, Vol 130, Issue 1, Page 83-92, (November 2003) Full article |
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Augustsson, H.; Van der Weerd, H.A.; Kruitwagen, C.L.J.J.; Baumans, V. 'Effect of enrichment on variation and results in the light/dark test' Laboratory Animals (2003), Vol 37, Page 328-340, (October 2003) Full article |
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Quinn, L.; Steann, T.; Trail, B.; Duxon, M.; Stratton, S.; Billinton, A.; Upton, N. 'Validation of LABORAS using various dopaminergic manipulations including MPTP-induced Nigro-striatal degeneration in mice' Poster presented at AD/BP (Alzheimer's & Parkinson's Diseases) conference in Seville Spain, 8-11 May 2003 |
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Kramer, K.; Kinter, L. 'Evaluation and applications of radiotelemetry in small laboratory animals (review)' Physiol Genomics, Vol 13, Page 197-205, (February 2003) Full article |
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Quinn, L.; Steann, T.; Trail, B.; Duxon, M.; Stratton, S.; Billinton, A.; Upton, N. 'LABORAS: pharmacological validation of a system allowing continuous monitoring of animal behaviour' Poster presented at Society for Neuroscience meeting in Orlando, Nov. 2002 |
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Wilson, A. 'Assessing Rodent Wellbeing': Report of the 2001 RSCPA / UFAW Rodent Welfare Group meeting Animal Technology and Welfare, April 2002 |
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Quinn, L.; Steann, T.; Trail, B.; Wilson, A.; Bulthuis, R.; Schekkerman, A.; Upton, N. 'LABORAS System Validation: Using Orexin-A Induced Grooming' GSK Poster Poster |
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Van der Meer, M. 'Transgenis and Animal Welfare - Implications of transgenic procedures for the well-being of the laboratory mouse' Thesis M. van der Meer, Utrecht, NL (October 4, 2001) Full report |
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Van der Meer, M.; Rolls, A.; Baumans, V.; Olivier, B.; Van Zutphen, L.F.M. 'Use of score sheets for welfare assessment of transgenic mice' Laboratory Animals, Vol 35, Issue 4, Page 379-389(11), October 2001 Full article |
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Van der Meer, M.; Baumans, V.; Olivier, B.; Kruitwagen, C.; Van Dijk, J.; Van Zutphen, L.F.M. 'Behavioural and physiological effects on biotechnology procedures used for gene targeting in mice' Physiology and Behavior, Vol 73, Issue 5, Page 719-730, August 2001 Full article |
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Baumans, V.; Bouwknecht, J.A.; Boere H.; Kramer, K.; Van Lith, H.A.; Van de Weerd, H.A.; Van Herck, H. 'Intra-abdominal transmitter implementation in mice: effects on behaviour and body weight.' Animal Welfare, Vol 10, Issue 1, Page 291-302, August 2001 |
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Van der Meer, M.; Baumans, V.; Olivier, B.; Kruitwagen, C.; Van Dijk, J.; Van Zutphen, L.F.M. 'Impact of transgenic procedures on behavioral and physiological responses in post-weaning mice' Physiology and Behavior, Vol 73, Issue 1-2, Page 133-14, May 2001 Full article |
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Van Herck, H.; Baumans, V.; Brandt, C.J.W.M.; Boere, H.A.G.; Hesp, A.P.M.; Van Lith, H.A.; Schurink, M.; Beyen, A.C.; 'Blood sampling from the retro-orbital plexus, the saphenous vein and the tail vein in rats: comparative effects on selected behavioural and blood variables.' Laboratory Animals (2001) Vol 35, Page 131-139. Full article |
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Van de Weerd, H.A.; Bulthuis, R.J.A.; Bergman, A.F.; Schlingmann, F.; Tolboom, J.; Van Loo, P.L.P.; Remie, R.; Baumans, V.; Van Zutphen, L.F.M. 'Validation of a new system for automatic registration of behaviour in mice and rats.' Elsevier Behavioral Processes, Vol 53, Issue 1-2, March 2001 Full article |
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Krohn, T.C.; Hejgaard, K.; Kornerup Hansen, A. 'Methods for general assessment of the welfare of laboratory animals' Acta Agriculture, Section A - Animal Science, Vol 51, Supplement 30, Page 118-123, Februari 2001. |
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Tanja Schubb 'Automated Systems for Analysis of Rodent Activity and Behavior' Article in Lab Animal, January 2001. |
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Kramer, K. 'Applications and Evaluation of Radio-Telemetry in small Laboratory Animals.' Thesis K. Kramer (ISBN: 90-393-2313-5), Utrecht, NL, April 2000 |
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Van Herck, H.; Baumans, V.; Boere, H.A.G.; Hesp, A.P.M.; Van Lith, H.A.; Beynen, A.C. 'Orbital Puncture in Rats: Effects upon Selected Behavioural Variables.' Publication in Laboratory Animals, 1999 . |
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Schlingmann, F.; Van de Weerd, H.A.; Baumans, V.; Remie, R.; Van Zutphen, L.F.M. 'A balance device for the analysis of behavioural patterns of the mouse.' Publication in Animal Welfare, 7, 177-188, 1998 |
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Leenaars, P.P.A.M.; Koedam, M.A.; Wester, P.W., Baumans, V.; Claassen, E.; Hendriksen, C.F.M. 'Assessment of side effects induced by injection of different adjuvant/antigen combinations in rabbits and mice.' Laboratory Animals (1998) 32, 387-406 Full article |
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Van de Weerd, H.A. 'Environmental Enrichment for Laboratory Mice: Preferences and Consequences' Thesis H.A. van de Weerd, Utrecht, NL (November 22, 1996) |
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Baumans, V.; Schlingmann, F.; Van de Weerd, H.A.; Remie, R.; Van Zutphen, L.F.M. 'Development of a balance system for analysis of rodent behaviour.' Proceedings Measuring Behaviour '96, Utrecht, NL, Oct. 1996 |
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Dept. of Laboratory Animal Science, Solvay Duphar, Weesp, NL Dept. of Laboratory Animal Science, Utrecht University, NL Metris System Engineering, Wassenaar, NL 'Automated Behaviour Classification: The LABORAS Project' Proceedings of the Sixth Felasa Symposium, Basel, CH, June 1996 |